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目的探讨男性尿路感染的易感因素,致病菌的分布及其耐药情况,为临床治疗提供依据。方法对189例尿培养阳性的男性尿路感染患者的易感因素、尿培养及其药敏试验结果进行回顾性分析。结果189例男性尿路感染患者,复杂性尿感占87．83%。易感因素以留置尿管、前列腺疾病、尿路结石为主。205株致病菌中革兰氏阴性杆菌占61．95%。其中大肠杆菌占30．73%；革兰氏阳性球菌占17．07%；真菌占20．98%。从药敏试验得出,所有菌株耐药率最低的是亚胺培南,其次为阿米卡星、哌拉西林/他唑巴坦。肠球菌对氨苄西林有中度敏感性,重症肠球菌感染可首选万古霉素。有尿路操作者真菌和变形杆菌感染率明显高于无尿路操作者(P＜0．01)。结论男性尿路感染以复杂性尿感为主,主要致病药仍是革兰氏阴性杆菌,并以大肠杆菌为主,真菌感染有上升趋势,临床中应引起重视。
Objective To investigate the predisposing factors, pathogenic bacteria distribution and drug resistance in male urinary tract infection, and to provide basis for clinical treatment. Methods A retrospective analysis was made on the susceptibility factors, urinary culture and drug susceptibility test results of 189 urinary tract infection-positive men with urinary tract infection. Results 189 cases of urinary tract infection in patients with complicated urinary tract accounted for 87.83%. Susceptibility factors to indwelling catheter, prostate disease, urinary tract stones. Among the 205 pathogenic bacteria, Gram-negative bacilli accounted for 61.95%. Escherichia coli accounted for 30.73%; Gram-positive bacteria accounted for 17.07%; fungi accounted for 20.98%. According to the drug susceptibility test, the lowest resistance rates of all the strains were imipenem, followed by amikacin and piperacillin / tazobactam. Enterococci have a moderate sensitivity to ampicillin, vancomycin can be the preferred enterococcal infection. In urinary tract operators fungal and Proteus infection rates were significantly higher than those without urinary tract surgery (P <0.01). Conclusions Male urinary tract infection is mainly complicated urinary tract infection, and the main pathogenic drug is still Gram-negative bacilli. Escherichia coli is the main pathogenic agent, and fungal infections are on the rise. Clinicians should pay attention to it.