坂本氏等10年前报告了阵发性房颤固定化发生率在一年之内为25％,并指出该发生率与有基础疾病等患者背景有相当大的差别。例如,Parkioson氏等报告在风湿性瓣膜病2年中50％房颤变为永久性的,而在孤立性房颤观察4年只有10％。为此,坂本等研究了基础疾病种类、年龄与阵发性房颤的关系。其对象是1969年以后22年中受诊的阵发性房颤227例、经初诊至1年以上观察心电图经过者158例(男116例、女42例、平均年龄62.1岁) 结果:一年之内阵发性房颤固定率为28％,与10年前数值大致相同。在这些阵发性房颤固定率中无基础疾病即孤立性房颤最多占39％,其次是高血压性心 Sakamoto et al 10 years ago reported a fixed incidence of paroxysmal atrial fibrillation in 25% within a year, and pointed out that the incidence and underlying diseases such as patients with a considerable background. For example, Parkioson et al. Reported that 50% of patients with atrial fibrillation became permanent in 2 years of rheumatic valvular disease and only 10% in 4 years of isolated atrial fibrillation. To this end, Sakamoto studied the basic types of diseases, age and paroxysmal atrial fibrillation. The object is 227 cases of paroxysmal atrial fibrillation (ADR) diagnosed in 22 years after 1969. 158 cases (116 males and 42 females, average age 62.1 years) were observed after more than one year after initial diagnosis. Results: One year The rate of paroxysmal atrial fibrillation was 28%, about the same as 10 years ago. In these paroxysmal atrial fibrillation fixed rate no underlying disease that isolated atrial fibrillation up to 39%, followed by hypertensive heart