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癌肿局部复发是大肠癌手术后死亡的主要原因,英国的结、直肠癌患者行切除手术后局部复发率约为14％,约80％病冽系术后2年发生癌肿局部复发,其中多数人不能施行进一步的“治疗”手术。临床和实验研究表明局部复发可能来自存活的脱落癌细胞术中转移,重建吻合口所用的缝合材料亦可能在此机理中发生作用,通常称作种植转移。为了研究脱落癌细胞的缝线种植所导致大肠癌局部复发,作者分别比较聚酰胺编织线,聚乙二醇编织线,聚丙烯单丝和不锈钢单丝4种缝合材料网罗和转运鼠结肠腔内游离癌细胞的
Local recurrence of cancer is the main cause of postoperative death in colorectal cancer. The local recurrence rate in patients with colorectal cancer in the UK is approximately 14% after resection. About 80% of the disease patients have local recurrence of cancer within 2 years after surgery. Most people can not perform further “treatment” surgery. Clinical and experimental studies suggest that local recurrence may result from intraoperative metastases of surviving exfoliative cells, and suturing materials used to reconstruct anastomosis may also play a role in this mechanism, commonly referred to as implant metastasis. In order to study the local recurrence of colorectal cancer caused by the sutures of exfoliated cancer cells, the authors compared the braided cords, polyethylene glycol braided cords, polypropylene monofilaments, and stainless steel monofilaments, respectively, to the meshing and transport of intramucosal lumens. Free cancer cells