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Background Systemic-to-pulmonary shunt (SPS) is an effective surgery for newbos diagnosed with atresia or severe pulmonary stenosis leading to insufficient pulmonary blood flow.However,there is no consistent conclusion on surgical plan chosen for the particular patient.Methods Shunt configurations including central shunt (CS) and MBTS (Right mbT innominate;Left mBT subclavian) were virtually reconstructed for newbo based on preoperative CT data.Candidate shunt configurations were evaluated based on the parameters that were computed from the flow simulations.Results Vortex occurred at the anastomosis of the shunt and the aorta for all three shunt configurations.For CS,it produced the highest pulmonary artery (PA) flow,with the shunt ratio of 44,.6%.Blood flow in LPA was 8.5% higher than blood flow in RPA.For MBTS,the indexed power loss (iPL)of Right mBT innominate configuration was lower than that of Left mBT subclavian,which was 28.4% and 36.1% respectively.Conclusions The anastomosis of the shunt and the aorta is prone to cause thrombosis.CS configuration is prone to cause hyperemia due to excessive pulmonary blood flow.So,it could be considered for patients without a risk of overflow.It also causes non-symmetric PA flow in favor of LPA.For Right mBT innominate,which has the lowest iPL,tends to produce smaller vortex regions compared to CS and Left mBT subclavian.As for Left mBT subclavian,vortex currents formed when blood flows into the LPA could prevent the formation of thrombosis.