石棉是一组天然矿物纤维的总称。长期接触石棉可引起肺癌及间皮瘤。自从提出石棉与肺癌的关系以来，人们利用体内和体外实验系统，从石棉纤维的物理特性、化学组成、细胞毒性、遗传毒性、癌基因及抑癌基因等多方面，从机体、细胞、生化、分子等多层次来探讨石棉的致癌机制... Asbestos is a group of natural mineral fibers. Long-term exposure to asbestos can cause lung cancer and mesothelioma. Since the establishment of the relationship between asbestos and lung cancer, people have used many in vitro and in vivo experimental systems to study the relationship between asbestos and lung cancer, from physical, chemical composition, cytotoxicity, genotoxicity, oncogenes and tumor suppressor genes of asbestos fibers, Molecular and other levels to explore carcinogenic mechanism of asbestos ...