血管瘤(Hemangioma,HA)为小儿常见的良性肿瘤,发病率为1%～2%。血管瘤轻者影响人体的解剖结构和生理功能,造成畸形及容貌缺陷,严重者可危及生命。其病因仍不清楚,近年研究表明多种因素与血管瘤增生发展有关,研究进展包括以下方面。1血管形成因子1.1血管内皮生长因子(Vascular e Hemangioma (HA) is a common benign tumor in children, the incidence of 1% to 2%. Hemangiomas affect the anatomy and physiology of the human body, resulting in deformity and appearance defects, serious cases can be life-threatening. The etiology is still not clear, recent studies have shown that many factors related to the proliferation and development of hemangiomas, research progress includes the following aspects. 1 angiogenic factor 1.1 vascular endothelial growth factor (Vascular e