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对6例原发性线粒体肌病者及4例正常对照的骨骼肌线粒体进行电镜形态计量学研究。线粒体肌病患者线粒体截面的周长、面积及圆偏度显著大于正常人;线粒体比表面显著低于正常人,线粒体比表面与静态血乳酸水平及血乳酸丙酮酸比值呈显著负相关。
Six cases of primary mitochondrial myopathy and four normal control skeletal muscle mitochondria were observed by electron microscopy. Mitochondrial cross section of mitochondria in patients with mitochondrial perimeter, area and roundness were significantly greater than normal; mitochondrial specific surface was significantly lower than normal, mitochondrial specific surface and the level of serum lactate and blood lactate pyruvate ratio was significantly negatively correlated.