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目的探讨经蝶垂体瘤切除术后低钠血症的临床过程及其特点。方法回顾分析经蝶垂体瘤切除术后低钠血症患者11例。结果经蝶垂体瘤切除60例,术后发生低钠血症11例(18.3%)。2例发生在术后第1天,其余9例发生在术后4~9d,属于迟发性低钠血症。血钠一般是先缓慢下降,而后大幅度降至最低点,平均124mmol/L(范围112~132mmol/L)。7例(64%)有头痛、恶心、呕吐、昏迷等合并症,但都短暂可逆。治疗主要包括限制液体入量和补充钠盐两方面。11例患者均在治疗后7d内血钠恢复正常。结论经蝶垂体瘤切除术后低血钠症的临床过程具有一定特点。若及时发现,正确治疗,均可很快恢复正常。
Objective To investigate the clinical course and characteristics of hyponatremia after transsphenoidal pituitary tumor resection. Methods Retrospective analysis of 11 cases of hyponatremia after transsphenoidal pituitary tumor resection. Results The transsphenoidal pituitary tumor was resected in 60 cases and hyponatremia in 11 cases (18.3%). 2 cases occurred on the first postoperative day, the remaining 9 cases occurred 4 to 9 days after surgery, is a delayed type of hyponatremia. Serum sodium is generally slowly decreased first, and then dropped to the lowest point, with an average of 124mmol / L (range 112 ~ 132mmol / L). 7 cases (64%) had headache, nausea, vomiting, coma and other complications, but are transiently reversible. The treatment mainly includes the limitation of fluid intake and the supplement of sodium salt. Eleven patients returned to normal within 7 days after treatment. Conclusion The clinical course of hyponatremia after transsphenoidal pituitary tumor resection has certain characteristics. If found in time, the correct treatment, can quickly return to normal.