片剂是一种最常用的药物剂型,崩解是片剂的重要物理性质之一,也是药物溶出速率的其中一项指标。崩解的难易直接影响到片剂的质量和生物利用度。目前各国药典对片剂的质量要求,几乎都有崩解度的检查。我国和美国、英国等国家还要求对某些药进行溶出速率的检查。近年来对片剂崩解度的 Tablets are one of the most commonly used pharmaceutical dosage forms and disintegration is one of the important physical properties of the tablets and one of the drug dissolution rates. The difficulty of disintegration directly affects the quality and bioavailability of the tablets. At present, the quality requirements of each country’s pharmacopoeia tablet, almost all have disintegration degree of inspection. China and the United States, Britain and other countries also require the dissolution rate of certain drugs check. In recent years the tablet disintegration degree