目的：介绍国内外熔融高速搅拌制粒的影响因素和成粒机制的研究。方法：以文献为基础，从原料特性、粘合剂、投料量、搅拌桨及切割桨速度、加热温度、制粒时间以及冷却速度等因素对粒子大小、粒度分布等粒子特性的影响进行归纳总结。结果：通过对各因素的量化控制，可以优化处方和工艺，得到理想的粒子。结论：熔融高速搅拌制粒具有广阔前景 Objective: To introduce the influencing factors and granulation mechanism of high-speed stirred granulation at home and abroad. Methods: Based on the literature, the effects of particle size, particle size distribution and other characteristics on particle properties were summarized based on the characteristics of raw materials, binder, feeding amount, stirring paddle and cutting paddle speed, heating temperature, granulation time and cooling rate . Results: Through the quantitative control of various factors, prescriptions and processes can be optimized to obtain the desired particles. Conclusion: Melting high-speed mixing granulation has broad prospects