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本文综述了近10年来从中草药和天然药物中发现的抗病毒活性成分的概况及其作用原理。这些活性成分包括生物碱,黄酮,萜和挥发油,甙,醇、醛、醌和内酯,蛋白质、多肽、氨基酸,有机酸,鞣质,单、多糖以及维生素,核酸,胆色素等。在作用原理上,它们或作用于病毒的增殖过程,或影响宿主细胞和宿主的屏障,有的则干扰病毒和宿主细胞的相互作用,特别在黄酮、鞣质等抗病毒作用的构效关系上有所发展。
This article reviews the overview of the antiviral active ingredients found in Chinese herbal medicines and natural medicines in the past 10 years and their working principles. These active ingredients include alkaloids, flavonoids, glycosides and volatile oils, alfalfa, alcohols, aldehydes, oximes and lactones, proteins, peptides, amino acids, organic acids, tannins, monosaccharides, polysaccharides and vitamins, nucleic acids, bile pigments, and the like. In principle, they either act on the proliferation process of the virus or affect the barriers of the host cell and the host, while others interfere with the interaction between the virus and the host cell, especially on the structure-activity relationship of the antiviral action of flavonoids, tannins, etc. Have some development.