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应用COPT、IHA、ELISA检测新流行区44例血吸虫病人吡喹酮治疗前后抗体水平变化。结果,治后6个月,COPT、IHA和ELISA的抗体阴转率分别为47.7％、9.1％和22.7％;环沉率均值由治前27.3％下降至9.9％,IHA和ELISA检测的抗体滴度均有明显下降,治后12个月COPT的阴转率较IHA、ELISA为高,但治后12～18个月3法检测的抗体水平未见继续下降。感染度较高(EPG≥16)的23例患者,治前3法阳性率均为95.7％,治后6月、12个月抗体水平下降幅度COPT明显高于IHA和ELISA。在新流行区COPT近期疗效考核的效果比IHA和ELISA为好。
The levels of antibodies in 44 schistosomiasis patients treated with praziquantel before and after treatment with COPT, IHA and ELISA were measured. As a result, the antibody negative conversion rates of COPT, IHA and ELISA were 47.7%, 9.1% and 22.7% respectively at 6 months after treatment; the mean values of ECAP decreased from 27.3% to 9.9% Degrees, the negative conversion rate of COPT was higher than that of IHA and ELISA at 12 months after treatment, but the level of antibody detected by method 3 did not decrease further after 12-18 months of treatment. In the 23 patients with higher infection (EPG≥16), the positive rate of preeclampsia 3 was 95.7%. The reduction of antibody levels at 6 months and 12 months after treatment was significantly higher than that of IHA and ELISA. In the new endemic area COPT recent efficacy assessment results better than IHA and ELISA.