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目的 探讨老年男性与泌尿生殖系有关的多原发恶性肿瘤的临床意义。 方法 1972年 1月至 1999年 12月收治与泌尿生殖系有关的多原发恶性肿瘤男性患者 41例 ,其中老年患者 2 4例 ,对其进行回顾性分析。 结果 与泌尿生殖系有关的多原发恶性肿瘤患者占同期泌尿生殖系恶性肿瘤患者的 4 8% ,其中老年患者占 5 8 5 %。 2 4例老年患者平均患病年龄为 73岁 ,第一癌与第二癌平均间隔为 2 3年。泌尿生殖系统与消化系统最为常见 ,第一癌前者占 75 % ,后者占 17% ;第二癌前者占 46 % ,后者占 2 9%。 2 3例获得随访 ,随访中位时间 3 5年 ,14例死亡 ,直接死因为第二癌者 12例。 结论 多原发恶性肿瘤在泌尿外科并不少见 ,应重视对第二癌的诊疗 ,这对老年人生活质量的改善有重要意义。
Objective To investigate the clinical significance of multiple primary malignant tumors associated with genitourinary in elderly men. Methods From January 1972 to December 1999, 41 cases of multiple primary malignant tumors associated with genitourinary tract were admitted to our hospital, including 24 elderly patients. Retrospective analysis was carried out. Results The majority of patients with multiple primary malignant tumors related to genitourinary tract accounted for 48% of the patients with genitourinary malignancies during the same period, of which, 58.5% were elderly patients. The average age of illness in 24 elderly patients was 73 years. The average interval between the first and second cancers was 23 years. The genitourinary system and digestive system are the most common, with the first carcinogen accounting for 75%, the latter accounting for 17%, the second cancerogenic accounting for 46% and the latter accounting for 29%. Twenty-three patients were followed up for a median of 35 years. Fourteen patients died of secondary cancer and 12 were secondary cancer. Conclusions Multi-primary malignancies are not uncommon in urology and attention should be paid to the diagnosis and treatment of secondary cancers, which is of great significance for the improvement of quality of life in the elderly.