支气管肺发育不良(BPD)指早产儿生后因各种疾病引起呼吸衰竭需机械通气治疗,终致氧气依赖、胸片异常及呼吸道症状持续超过28天者。其发病机理如图示。随着NICU的发展,危重新生儿、特别是极低体重儿成活率逐年增加,与之相关的BPD,发病率也相应增加。鉴于BPD患儿有较高 Bronchopulmonary dysplasia (BPD) refers to premature infants due to various diseases caused by respiratory failure requiring mechanical ventilation treatment, eventually leading to oxygen dependence, chest X-ray abnormalities and respiratory symptoms continued for more than 28 days. The pathogenesis as shown. With the development of NICU, the survival rate of critically ill newborns, especially those with very low birth weight, has been increasing year by year. The incidence of BPD associated with it has also increased accordingly. Given the high BPD children