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肝昏迷是肝病的一个危重并发症,死亡率颇高。近年来国内外学者在研究其发病机制和有效治疗方面,已取得可喜的进展。本文笔者参阅近期文献,结合临床实际,对肝昏迷的治疗概述如下,供参考。由于肝昏迷的发病机制是多方面的,所以应采取综合治疗为宜。目前治疗仍限于支持、对症及防止并发症方面,而关键在于针对氨中毒的治疗,这不仅需要控制肠道内氨的来源,减少氨的生成与吸收,同时还需应用脱氨药物,才能收到较好的效果。
Hepatic coma is a serious complication of liver disease with high mortality. In recent years, domestic and foreign scholars have made gratifying progress in studying their pathogenesis and effective treatment. The author of this article refer to recent literature, combined with clinical practice, the treatment of hepatic coma is summarized as follows for reference. As the pathogenesis of hepatic coma is multifaceted, it is appropriate to take comprehensive treatment. The current treatment is still limited to support, symptomatic and prevent complications, and the key is for the treatment of ammonia poisoning, which not only need to control the source of ammonia in the intestine to reduce the formation and absorption of ammonia, but also the need to use deamination drugs, to receive Better effect.