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一些艾滋病患者常有痛觉过敏的咽部溃疡,在很大程度上可影响营养的摄入及导致全身情况的恶化。除巨细胞病毒感染所致的下消化道溃疡外,此种溃疡的原因不详。此种感染使用大剂量的吗啡亦不能完全解除疼痛。最近作者用酞胺哌啶酮治疗3例伴有咽部溃疡的艾滋病患者,结果溃疡完全消失并于短期内治愈。当酞胺哌啶酮的致畸作用被阐明后,其作为镇静剂使用未得到临床重视。最近在严格的试验条件下已将其应用于治疗麻风、重症痒疹
Some people with AIDS often have hyperalgesia pharyngeal ulcers, which can largely affect nutrient intake and lead to the deterioration of the general condition. In addition to cytomegalovirus infection caused by lower gastrointestinal ulcers, the reasons for such ulcers is unknown. This infection with high doses of morphine can not completely relieve pain. Recently, the authors used thalidomide to treat 3 AIDS patients with pharyngal ulcers, with the result that the ulcer disappeared completely and was cured within a short period of time. When thalidomide has teratogenicity elucidated, its use as a sedative has not been clinically valued. It has recently been applied to the treatment of leprosy, severe prurigo under rigorous experimental conditions