交沙霉素属于大环内酯类抗生素，依照卫生部药品标准［１］（以下简称部标法）测定效价发现，菌层生长稀薄，抑菌圈边缘欠清晰，呈微锯齿状，且双圈明显，用游标卡尺或抑菌圈测量仪测量会引起较大误差。本文对部标法作了改进，在培养基制备时添加一定比例的葡萄糖，克服了上述 Josamycin is a macrolide antibiotic, according to the Ministry of Health drug standards [1] (hereinafter referred to as the ministerial method) determination of potency found that the growth of thin layer of bacteria, bacteriostatic edge margin is not clear, was jagged, and Double clear, measured with a vernier caliper or zone of inhibition measuring instrument will cause greater error. In this paper, the standard method has been improved, in the medium preparation to add a certain percentage of glucose, to overcome the above