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目的探讨低级别子宫内膜间质肉瘤(low grade-endometrial stromal sarcoma,LG-ESS)的临床、病理及治疗特点,为临床提供指导。方法检索我院5年间LG-ESS病例,以检出的46例LG-ESS病例为基础,总结疾病特点,并回顾相关文献。结果 46例患者多数无症状,8例月经改变,7例腹部不适,1例腹部增大、排尿困难及便秘。44例初次手术前考虑为良性疾病,最终术后诊断为早期LG-ESS,其他1例为ⅡB期,1例为Ⅳ期;最终1例患者复发,复发后再次手术,无瘤存活至今。结论 LG-ESS临床及病理特征不突出,妇产科及病理科对该病认识不足,应加强总结及分析,减少贻误。
Objective To investigate the clinical, pathological and therapeutic features of low-grade endometrial stromal sarcoma (LG-ESS) and provide guidance for clinical practice. Methods We searched LG-ESS cases in our hospital for 5 years and based on the detected 46 cases of LG-ESS, summarized the characteristics of the disease and reviewed the related literatures. Results Most of the 46 patients were asymptomatic, with 8 cases of menstruation, 7 cases of abdominal discomfort, 1 case of abdominal enlargement, dysuria and constipation. Forty-four patients were considered as benign disease before the first operation. The final diagnosis was early postoperative LG-ESS, the other 1 case was stage IIB, and the other 1 case was stage IV. Finally, one patient relapsed and reoperated, and the tumor survived so far. Conclusion The clinical and pathological features of LG-ESS are not conspicuous. Obstetrics and gynecology and pathology are not aware of the disease. Therefore, the summary and analysis of LG-ESS should be strengthened to reduce the amount of adverse effects.