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目的探讨布地奈德/福莫特罗与氨溴索联合雾化吸入在支气管哮喘患者中的效果。方法选择我院2010年8月至2012年8月支气管哮喘患者共60例,所选患者均给予布地奈德/福莫特罗粉吸入,每次吸入剂量为布地奈德(160μg)/福莫特罗(4.5μg),每天吸入4次,早晨和晚上各2次,连续吸入1个月后减为每天早晨吸入1次,晚上吸入2次,2个月后剂量减少为早晨和晚上各吸入1次。在给予布地奈德/福莫特罗粉吸入时,同时给予氨溴索注射液30 mg雾化吸入,2次/d。患者吸入后给予清水漱口。结果治疗3个月后日间哮喘症状评分均低于治疗1个后评分和治疗2个月后评分,差异有统计学意义(P<0.05)。治疗3个月后患者肺功能较治疗前、治疗1个月和治疗2个月时得到显著改善,差异有统计学意义(P<0.05)。结论布地奈德/福莫特罗与氨溴索联合雾化吸入能够显著改善支气管哮喘患者临床症状,改善肺功能,值得借鉴。
Objective To investigate the effect of inhalation of budesonide / formoterol combined with ambroxol on bronchial asthma patients. Methods A total of 60 patients with bronchial asthma were selected from August 2010 to August 2012 in our hospital. All the patients were given budesonide / formoterol powder inhalation. The inhaled dose was budesonide (160 μg) Tropsch (4.5 μg), inhaled 4 times a day, twice daily in the morning and evening, inhaled for 1 month after continuous inhalation reduced to 1 inhalation every morning and 2 inhaled at night, and reduced to morning and evening inhalation after 2 months 1 time. In the given budesonide / formoterol powder inhalation, given ambroxol injection 30 mg inhalation, 2 times / d. Patients were given clear water after inhalation mouthwash. Results The scores of daytime asthma symptoms after 3 months of treatment were all lower than those of 1 case after treatment and 2 months after treatment. The difference was statistically significant (P <0.05). The lung function of patients after 3 months of treatment was significantly improved compared with before treatment, 1 month of treatment and 2 months of treatment, the difference was statistically significant (P <0.05). Conclusion Combined inhalation of budesonide and formoterol with ambroxol can significantly improve clinical symptoms and improve pulmonary function in patients with bronchial asthma.