从生态学的观点出发,生物体并非是独立的个体,而是和体内、体表的其它微生物共同组成的群体,即自然生态系的复合体。六十年代初期便发现甘薯和果树体内带菌(陈延熙),1963年勒凯发表了《无菌生命和动物的熟知菌培养》,1973年哈策发表了《植物的熟知菌培养》,都是对生物体内带菌现象的初步认识。最近,医学界米契尔专著“消化道中的微生物代谢”,对消化道中微生物与健康和疾病的关系进行了系统的研究。 From the ecological point of view, organisms are not independent individuals, but with other microorganisms in the body, the body surface composed of groups, that is, a complex of natural ecosystems. In the early 1960s, sweet potato and fruit trees were found to be in vivo (Chen Yanxi). In 1963, Lekai published “Aseptic Bacteria and Animal Cultivation”. In 1973, Preliminary understanding of the phenomenon of bacteria in living body. Recently, Misic’s book Microbial Metabolism in the Digestive Tract, a systematic review of the relationship between microorganisms in the digestive tract and health and disease, has been conducted.