目的探讨多学科综合治疗对原发性支气管肺癌的生存影响。方法回顾性分析324例原发性支气管肺癌的患者资料。其中,鳞癌117例,占36.1%;腺癌102例,占31.6%;腺鳞癌63例,占19.2%;大细胞癌23例,占7.2%;小细胞未分化癌19例,占5.7%。Ⅰ期41例,Ⅱ期138例,Ⅲ期121例,Ⅳ期24例。结果手术切除287例,占88.6%,探查37例,占11.7%。围手术期手术死亡5例,病死率1.5%。术后化疗组147例,3、5年生存率为49.3%、29.9%,术后未化疗组131例,3、5年生存率为1.6%、23.1%,差异有统计学意义(P<0.05)。结论重视肺癌的诊断和治疗、充分的术前准备、合理选择手术时机与手术方式、加强术中与术后监测和防治并发症,是减少术后并发症和病死率、提高根治性切除率、生存率和改善生存质量的关键。 Objective To investigate the multidisciplinary comprehensive treatment of primary bronchial lung cancer survival impact. Methods The data of 324 patients with primary bronchogenic carcinoma were retrospectively analyzed. There were 117 cases of squamous cell carcinoma (36.1%), 102 cases of adenocarcinoma (31.6%), 63 cases of adenosquamous carcinoma (19.2%), 23 cases of large cell carcinoma (7.2%), 19 cases of small cell undifferentiated carcinoma %. 41 cases were stage Ⅰ, 138 cases were stage Ⅱ, 121 cases were stage Ⅲ and 24 cases were stage Ⅳ. Results Surgical resection of 287 cases, accounting for 88.6%, exploration of 37 cases, accounting for 11.7%. Perioperative death in 5 cases, the mortality rate of 1.5%. In the postoperative chemotherapy group, 147 cases had a 3.5-year and 3.5-year survival rates of 49.3% and 29.9% respectively. There were 131 cases in the non-chemotherapy group and 1.6 and 23.1% in 3 and 5-year postoperative chemotherapy, respectively (P <0.05 ). CONCLUSIONS: Attention should be paid to the diagnosis and treatment of lung cancer, adequate preoperative preparation, proper selection of operation timing and operation mode, strengthening intraoperative and postoperative monitoring and prevention and treatment of complications, which are to reduce postoperative complications and mortality, to improve radical resection rate, Survival and the key to improving quality of life.