目的探讨围绝经期妇女的症状特征以及对相关知识的认知情况。方法 2013年7月至11月,在新疆医科大学第一附属医院妇科及体检中心,对454例围绝经期妇女进行问卷调查。对汉族与少数民族、不同文化程度、不同经济水平妇女的症状特征、知识知晓、治疗意愿等方面进行比较。采用χ2检验或Fisher确切概率法进行统计分析。结果 454例围绝经期妇女中,403例(88.8%)出现围绝经期症状,以烦躁、潮热出汗、失眠、疲乏和头疼最为常见;51例(11.2%)无相关症状。高中以上文化程度者,了解围绝经期发生原因的比例大于高中及以下文化程度者[47.1%(112/238)与22.2%(48/216)];月收入﹥2 000元者,了解围绝经期发生原因的比例大于月收入≤2 000元者[38.4%(117/305)与28.9%(43/149)]。知晓激素替代疗法的比例,汉族大于少数民族[27.1%(91/336)与12.7%(15/118)],高中以上文化程度者大于高中及以下文化程度者[31.5%(75/238)与14.4%(31/216)],月收入﹥2 000元者大于月收入≤2 000元者[30.2%(92/305)与9.4%(14/149)]。愿意接受激素替代疗法的比例,汉族大于少数民族[32.4%(109/336)与20.3%(24/118)],月收入﹥2 000元者大于月收入≤2 000元者[34.5%(100/305)与22.1%(33/149)]。结论应加强围绝经期妇女的随访、监测及相关知识普及,尤其是对文化程度较低、收入较低的妇女,以改善其生活质量。 Objective To investigate the symptom characteristics of perimenopausal women and their cognition of related knowledge. Methods From July to November 2013, 454 cases of perimenopausal women were surveyed in Gynecology and Physical Examination Center of the First Affiliated Hospital of Xinjiang Medical University. The comparison is made between the Han and ethnic minorities, women with different education levels and different economic levels, their symptoms, knowledge and treatment intention. Statistical analysis was performed using χ 2 test or Fisher exact test. Results Of the 454 perimenopausal women, 403 (88.8%) developed perimenopausal symptoms with irritability, hot flashes sweating, insomnia, fatigue and headache most commonly; 51 (11.2%) had no symptoms. Those with a high school education or above who understand the causes of perimenopausal periods are more likely than those with high school education or below [47.1% (112/238) vs. 22.2% (48/216)]; monthly income> 2,000 yuan The proportion of the causes was greater than the monthly income of ≤ 2000 yuan [38.4% (117/305) and 28.9% (43/149)]. Knowing the proportion of hormone replacement therapy, Han people were more than those of ethnic minorities [27.1% (91/336) vs 12.7% (15/118)], those with high school education more than those with high school education or below [31.5% (75/238) 14.4% (31/216)]. Those with monthly income> 2,000 yuan were more likely than those with monthly income ≤2,000 yuan [30.2% (92/305) vs 9.4% (14/149)]. The proportion of people who are willing to take hormone replacement therapy is greater than that of ethnic minorities [32.4% (109/336) vs 20.3% (24/118)], with a monthly income> 2,000 yuan and a monthly income of more than 2,000 yuan [34.5% (100 / 305) and 22.1% (33/149)]. CONCLUSIONS Follow-up, monitoring and dissemination of relevant knowledge should be strengthened for perimenopausal women, especially for women with lower education and lower income, in order to improve their quality of life.