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目的 探讨CT检查对判断新生儿缺氧缺血性脑病 (HIE)预后的价值。方法 对 85例HIE患儿分别在生后 1周内、2周～ 2个月、3～ 6个月、1～ 1 5岁进行CT检查 ;同时在生后12～ 14d进行新生儿行为神经测定 ;在 1～ 1 5岁测定发育商判断预后。结果 生后 1周内CT结果分度为重度者预后不良率为 4 0 9% (9/ 2 2 ) ,为中度者预后不良率为 5 7% (3/ 5 2 ) ;2个月时CT随访结果异常者预后不良率为 6 0 0 % (6 / 10 ) ;CT结果中度且 12～ 14d的NBNA评分≥ 35分与 <35分者的预后差异无显著性 ,CT结果重度且 12～ 14d的NBNA评分 <35分者有 72 7% (8/ 11)预后不良。结论 生后 1周内CT分度及生后 1个月左右随访结果 ,同时结合临床、生后 12～ 14dNBNA评分对判断HIE患儿的预后、制定治疗方案及疗程有重要意义。
Objective To investigate the value of CT examination in predicting the prognosis of neonatal hypoxic-ischemic encephalopathy (HIE). Methods Eighty-five HIE children underwent CT examination within 1 week, 2 weeks to 2 months, 3 to 6 months and 1 to 15 years after birth respectively. Behavioral neurons were also measured in neonates between 12 and 14 days after birth ; In 1 ~ 1 5 years old determined the prognosis of developmental providers. Results The rate of poor prognosis was 49% (9/2 2) in the first week after birth, and the poor prognosis was 57% (3/5 2). In 2 months The poor prognosis of CT was 6 0 0% (6/10). There was no significant difference in prognosis between moderate and 12-14 days NBNA score ≥35 and ≤35, CT was severe and 12 There were 72.7% (8/11) patients with NBNA scores <35 in ~ 14 days. The prognosis was poor. Conclusions Within 1 week after birth, CT grade and 1 month follow-up results, combined with clinical, postnatal 12 ~ 14dNBNA score to determine the prognosis of children with HIE, the development of treatment programs and courses of great significance.