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A newmethodofimmunizationwasdiscoveredintheearly 1990s .Severalresearchgroupsinde pendentlydemonstratedthatdirectinoculationofDNAplasmidscodingforaspecificproteinantigencouldelicitimmuneresponsesagainstthatanti gen[1 4 ] .SinceintheorythemRNAmoleculesalso
A new method of immunization was discovered in the early 1990s. Seventy-research group sinde pendently demonstrated that direct inoculation of DNA plasmids coding for specific protein in antigen-dependent immune response to cancer antigen gen [14] .inceintheorythemRNAmoleculesalso