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目的探究硝苯地平控释片治疗慢性肾功能不全合并高血压的临床效果。方法 73例慢性肾功能不全合并高血压患者,随机分为两组:试验组38例,选用硝苯地平控释片治疗;对照组35例,选用盐酸乐卡地平片进行治疗。比较两组患者的降压效果和并发症出现的情况。结果试验组的总有效率86.8%低于对照组的总有效率88.6%,但是比较差异无统计学意义(P>0.05),且试验组患者血肌酐值和尿素氮值与对照组比较差异无统计学意义(P>0.05),两种药对此种高血压的治疗效果相当。结论硝苯地平控释片治疗慢性肾功能不全合并高血压患者效果好,且经济实惠,可以广泛运用于临床上降压。
Objective To investigate the clinical effect of nifedipine controlled release tablets in the treatment of chronic renal insufficiency combined with hypertension. Methods Seventy-three patients with chronic renal insufficiency and hypertension were randomly divided into two groups: experimental group (n = 38) and nifedipine controlled release tablet (nifedipine controlled release tablet). The control group (n = 35) was treated with lercanidipine hydrochloride tablets. The antihypertensive efficacy and complications of the two groups were compared. Results The total effective rate of the experimental group was 86.8% lower than that of the control group (88.6%), but the difference was not statistically significant (P> 0.05). The serum creatinine and urea nitrogen of the experimental group were significantly lower than those of the control group Statistical significance (P> 0.05), two kinds of medicine for the treatment of hypertension is quite effective. Conclusion Nifedipine controlled release tablets in patients with chronic renal insufficiency and hypertension have good effect, and affordable, it can be widely used clinically to reduce blood pressure.