当前对高血压病的药物治疗不但要求能有效地控制血压,而且还要求改善靶器官的功能,因而寻求此类有效药物甚为重要。双氢吡啶类钙拮抗剂硝苯吡啶(NIF)和尼群地平(NIT)对外周血管有显著扩张作用,降压效果显著并可降低左室后负荷,已被选为治疗高血压病的一线药物,但其对逆转左室肥厚、改善左室舒缩功能研究得还很少,尤 The current medical treatment of hypertension not only requires effective blood pressure control, but also requires improving the function of target organs, and thus seeking such effective drugs is very important. Dihydropyridine calcium antagonists nifedipine (NIF) and nitrendipine (NIT) on peripheral blood vessels have a significant expansion, significant antihypertensive effect and can reduce left ventricular afterload, has been selected as the first line of treatment of hypertension Drugs, but its reverse the left ventricular hypertrophy, improve left ventricular systolic function of the study is still very small, especially