地尔硫(艹卓)是一种缓慢的钙通道阻滞剂,具有扩张冠状血管的效应,已被用于缺血性心脏病的治疗。但由于它有半衰期过短的缺点,所以心绞痛病人每天需服药三或四次。基于该病病程缓慢,为了获得稳定持久的药效,需要一种缓释剂型,使血药浓度维持在疗效水平,同 Diltiazem is a slow calcium channel blocker that has the effect of dilating coronary vessels and has been used in the treatment of ischemic heart disease. However, due to its short half-life shortcomings, patients with angina need to take three or four times a day. Based on the slow course of the disease, in order to obtain a stable and lasting efficacy, a sustained-release dosage form is needed to maintain the plasma concentration at the therapeutic level