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本文采用核T_3占据率(q％)代表血清T_3含量与核T_3受体的饱合程度,探讨消化道肿瘤病人血清T_3含量、q％和甲状腺激素(TH)生物效应指标三者之间关系。结果表明:消化道肿瘤病人血清T_3含量下降,TH生物效应常用指标——血清胆固醇含量变化不大,其原因可能系q％尚在正常范围内,血清T_3含量虽下降但不致引起TH生物效应指标的变化。
In this paper, nuclear T_3 occupancy rate (q%) is used to represent the serum T_3 content and saturation of nuclear T_3 receptor, and to explore the relationship among serum T_3 content, q% and thyroid hormone (TH) biological effect index of patients with digestive tract cancer. The results showed that serum T 3 levels in patients with digestive tract tumors decreased, and serum cholesterol levels, a commonly used index of TH biological effects, did not change very much. The reason may be that q% was still within the normal range, serum T 3 content decreased but it did not cause TH biological effects. The change.