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目的:观察疏血通注射液对慢性肺源性心脏病合并心房颤动患者的临床疗效。方法:68例患者随机分为观察组和对照组,每组34例。两组患者均常规给予低流量吸氧、化痰平喘、维持水电解质平衡、纠正酸碱平衡紊乱等对症支持处理,合并感染者根据病原学选择敏感的抗生素治疗,必要时采用无创呼吸机支持通气。观察组在对照组治疗的基础上应用疏血通注射液治疗14 d。观察两组患者的D-二聚体水平及血液流变学指标的变化。结果:治疗后观察组D-二聚体水平明显下降,血液流变学指标显著改善(P<0.05)。结论:疏血通注射液有助于改善慢性肺源性心脏病合并心房颤动的高凝状态,并可能降低心房颤动患者的血栓栓塞危险。
Objective: To observe the clinical effect of Shuxuetong injection on patients with chronic cor pulmonale complicated with atrial fibrillation. Methods: 68 patients were randomly divided into observation group and control group, 34 cases in each group. Two groups of patients were routinely given low-flow oxygen, phlegm and asthma to maintain water and electrolyte balance, correct acid-base balance disorders and other symptomatic supportive treatment, co-infected patients selected according to the pathogen sensitive antibiotics, if necessary, non-invasive ventilator support Ventilation. The observation group was treated with Shuxuetong injection on the basis of the control group for 14 days. D-dimer levels and hemorheological parameters of two groups were observed. Results: After treatment, the level of D-dimer in the observation group decreased significantly, and the indexes of hemorheology were significantly improved (P <0.05). Conclusion: Shuxuetong Injection can improve the hypercoagulability of chronic cor pulmonale complicated with atrial fibrillation, and may reduce the risk of thromboembolism in patients with atrial fibrillation.