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目的：以病理结果为金标准，探讨磁敏感加权成像（susceptibility weighted imaging, SWI）对脑胶质瘤术前分级的临床价值，并比较SWI的瘤体内磁敏感信号强度（intratumoral susceptibility signal intensity, ITSS）与动态磁敏感对比增强灌注成像（dynamic susceptibility contrast perfusion weighted imaging, DSC-PWI）序列的相对脑血容积（relative cerebral blood volume, rCBV）两个指标对胶质瘤术前分级的诊断效能。方法选取经手术病理证实并术前依次行常规MRI平扫、SWI、DSC-PWI及常规增强检查的41例脑胶质瘤患者临床影像资料，对扫描得出的SWI图像进行ITSS分级，PWI数据计算出rCBV值，分析相同层面的ITSS分级和rCBV值。分别比较ITSS分级及rCBV值与病理级别的差异性；分析ITSS分级、rCBV值和病理级别之间的相关性；分别评价两种方法对脑胶质瘤术前分级的诊断效能。结果 Kruskal-wallis检验提示ITSS分级在不同病理级别的胶质瘤中差异有统计学意义（P＜0.001）；Spearman相关分析显示ITSS分级与病理级别呈正相关（r=0.816， P＜0.001）；ANOVA检验显示rCBV值在不同病理级别的胶质瘤中差异有统计学意义（P＜0.001）。rCBV值与病理级别呈正相关（r=0.676，P＜0.001）；ITSS分级与rCBV值呈正相关（r=0.557，P＜0.001）。应用受试者工作特征（receiver operating characteristic, ROC）曲线显示ITSS分级与rCBV值对脑胶质瘤术前诊断均有较高的准确性。结论(1)ITSS分级、rCBV值与胶质瘤病理级别正相关；(2)SWI与DSC-PWI均可用于脑胶质瘤术前分级诊断，但SWI的ITSS级别诊断效能更高，且无需注射对比剂。“,”Objective To investigate the clinical value of susceptibility weighted imaging (SWI), in the preoperative grading of brain gliomas using the clinical and pathological results as the gold standard, and to comparatively study the diagnostic accuracies of intratumoral susceptibility signal intensity (ITSS) on SWI and relative cerebral blood volume (rCBV) on DSC-PWI in the preoperative grading of brain gliomas.Methods Clinical image data of forty-one patients with pathologically confi rmed brain gliomas who were admitted to our hospital were collected. In addition to conventional magnetic resonance imaging, pre- and post- contrast-enhanced SWI, DSC-PWI, contrast-enhanced seque nce were performed in all patients. The ITSS grade was determined and the rCBV value was calculated. The ITSS grade and rCBV value at the same level were analyzed.Results TheKruskal-wallis test showed significant difference in ITSS grade between the brain gliomas of different pathological grades (P<0.001); theSpearman corr elation analysis showed a positive correlation between ITSS grade and pathological grade (r=0.816,P<0.001); theANOVA test showed signifi cant difference in rCBV value between the brain gli omas of different pathological grades (P<0.001). There was a positive correlation between rCBV value and pathological grade (r=0.676,P<0.001); there was a positive correlation between ITSS grade and rCBV value (r=0.557,P<0.001). The receiver operating characteristic curve showed that ITSS grade and rCBV value had a high diagnostic accuracy for brain gliomas before operation.Conclusion (1)ITSS grade and rCBV value are correlated with pathological grade. (2)SWI can be used for preoperative grading of brain gliomas; both SWI and DSC-PWI have a high diagnostic accuracy, but ITSS grade of SWI have a higher diagnostic accuracy.