帕金森病是一种慢性神经退行性疾病,在临床上以震颤,肌肉强直,运动减少和姿势平衡障碍作为主要症状。目前主要以左旋多巴为代表的多巴胺替代治疗为主,但存在着药物副作用较多,不能阻止病情进展等不利因素。手术治疗在近年又有所发展,但也存在患者适应证有限,长期疗效较差等缺陷 Parkinson’s disease is a chronic neurodegenerative disease that is clinically characterized by tremor, muscular rigidity, decreased motion and posture balance disorders. At present, the main substitute of dopamine represented by levodopa is predominated, but there are many unfavorable factors such as more side effects of drugs and failure to stop the progress of the disease. Surgical treatment has been developed in recent years, but there are also shortcomings in patients with limited indications, long-term efficacy is poor