干燥综合征是一种以累及外分泌腺为主的慢性自身免疫性疾病，口、眼干燥和关节疼痛为其主要症状，并可伴多器官损伤。近年来临床认为，白细胞介素17(IL-17)在包括原发性干燥综合征在内的一些自身免疫性疾病的发病机制中起着关键作用。IL-17作为始动因子参与干燥综合征慢性炎性反应，可加剧组织损伤，促进病情进展。“,”Sjogren syndrome is a chronic autoimmune disease mainly involving exocrine glands. The main symptoms are dry mouth and dry eyes and joint pain, and can be accompanied by multiple organ damage, and which can be accompanied by multiple organ damage. In recent years, it is clinically believed that interleukin 17 (IL-17) plays a key role in the pathogenesis of some autoimmune diseases, including primary sjogren syndrome. IL-17 as an initiating factor participates in the chronic inflammatory reaction of sjogren syndrome, which can aggravate tissue damage and promote disease progression.