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目的:探讨阿托品拮抗异丙酚和芬太尼副反应并减少人流综合征及术后腹痛发生的可能机制。方法:选择600例早孕在40~80 d自愿要求无痛人流的孕妇随机分为试验组和对照组。试验组在实施人流中使用阿托品,对照组不用阿托品。结果:试验组与对照组相比差异有统计学意义(P=0.000),阿托品治疗有效。结论:阿托品能有效拮抗异丙酚和芬太尼引发的呼吸、循环抑制,有利于保证手术质量和安全性。
Objective: To explore the possible mechanisms by which atropine can antagonize side effects of propofol and fentanyl and reduce the incidence of post-operative abdominal pain and flow syndrome. Methods: A total of 600 pregnant women with early pain at 40-80 days were randomly divided into test group and control group. The experimental group used atropine in the implementation of abortion, while the control group did not use atropine. Results: The difference between the experimental group and the control group was statistically significant (P = 0.000), atropine treatment was effective. Conclusion: Atropine can effectively antagonize the respiration and circulation inhibition induced by propofol and fentanyl, which will help ensure the quality and safety of operation.