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目的探讨围孕期妇女叶酸及复合维生素B服用量与新生儿出生体质量的关系。方法采用分层多阶段随机抽样方法,选取辖区城区2016年1-12月妊娠妇女8186名,根据妇女围孕期营养素服用情况分组,其中围孕期服用过叶酸和维生素B者为A组(n=2182),围孕期仅服用叶酸者为B组(n=4022),围孕期未服用叶酸和维生素B者为C组(n=1982),采用多水平模型分析服用叶酸及复合维生素B与新生儿出生体质量的关系。结果各组妇女年龄、受教育年限、家庭月收入、初产比例,首次产检孕周≤13周、妊娠期产检<5次、妊娠期服用铁剂及妊娠期贫血比例比较差异有统计学意义(P<0.05);A组新生儿出生体重为(3340.21±160.50)g,明显高于B组和C组(P<0.05);B组新生儿出生体重为(3281.16±270.17)g,明显高于C组(P<0.05);Model O模型结果显示:A组新生儿出生体质量较B组和C组平均提高50 g和94 g,差异有统计学意义(P<0.05);Model 1模型结果显示:A组新生儿出生体质量较C组平均提高75 g,差异有统计学意义(P<0.05),A组新生儿出生体质量较B组平均提高22 g,差异无统计学意义(P<0.05)。结论围孕期妇女服用叶酸可提高新生儿出生体质量,复合维生素B对新生儿出生体质量无明显影响。
Objective To investigate the relationship between the intake of folic acid and vitamin B in pregnant women and the newborn’s birth weight. Methods Totally 8186 pregnant women in the district from January to December in 2016 were selected by stratified multistage random sampling method. Group A was divided into group A (n = 2182), taking folic acid and vitamin B as per group during pregnancy. ), Group B (n = 4022) taking folic acid during pregnancy only, group C taking folic acid and vitamin B during pregnancy (n = 1982), and taking multi-level model to analyze the effect of folic acid and vitamin B on the birth of newborns The relationship between body mass. Results The proportion of women in each group, age of education, monthly family income, proportion of first trimester, first trimester gestational week ≤13 weeks, pregnancy test <5 times, iron consumption during pregnancy and gestational anemia were statistically significant (P < P <0.05). The birth weight of newborns in group A was (3340.21 ± 160.50) g, which was significantly higher than those in groups B and C (P <0.05). The birth weight of newborns in group B was (3281.16 ± 270.17) g, (P <0.05). The results of Model O model showed that the birth weight of newborns in group A increased by 50 g and 94 g on average compared with that of group B and group C (P <0.05) The results showed that the birth weight of newborns in group A increased by 75 g on average compared with group C, the difference was statistically significant (P <0.05). The birth weight of newborns in group A was increased by 22 g on average compared with group B (P <0.05). Conclusions Folic acid can increase the birth weight of newborns in peri-pregnant women. There is no obvious effect of multivitamin B on the birth weight of newborns.