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目的探索米非司酮治疗中年功能失调性子宫出血的效果。方法确诊为功能失调性子宫出血,年龄40～55岁,无禁忌证,并自愿接受米非司酮治疗的患者60例,连续服用米非司酮治疗3～6个月,分别于治疗前、治疗后对照B超测量子宫内膜厚度,肝肾功能、血常规,随诊观察月经恢复情况及治疗效果。结果60例患者在服药期间均闭经,子宫内膜无增厚,肝肾功能正常,血红蛋白逐渐提高,贫血得到改善。结论米非司酮治疗中年功能性子宫出血,治疗效果满意,值得推广应用。
Objective To explore the efficacy of mifepristone in treating middle-aged dysfunctional uterine bleeding. Methods The diagnosis of dysfunctional uterine bleeding, aged 40 to 55 years old, no contraindications, and 60 cases of patients receiving mifepristone voluntarily, continuous taking mifepristone for 3 to 6 months, respectively, before treatment, After treatment, control B ultrasound measurement of endometrial thickness, liver and kidney function, blood, follow-up observation of menstrual recovery and treatment. Results All the 60 patients underwent amenorrhoea during the medication, no thickening of the endometrium, normal liver and kidney function, gradual increase of hemoglobin, and improvement of anemia. Conclusion Mifepristone treatment of middle-aged functional uterine bleeding, the treatment effect is satisfactory, it is worth to promote the application.