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结构性心脏病是指以心脏和大血管结构异常为主要表现的一大类心脏病，既包括先天性疾病也包括后天获得性疾病，主要包括先天性心脏病、获得性心脏瓣膜病和心肌病。近年来，结构性心脏病的介入手术治疗已逐渐成熟并广泛应用于临床。由于患者心脏瓣膜及瓣膜相关组织较为脆弱或先天性发育不良，加之手术复杂，介入手术操作可引起相关瓣膜损伤并发症，该文就结构性心脏病介入治疗相关的瓣膜损伤原因及其防治措施进行介绍。“,”Structural heart diseases refer to anatomic heart or great vessels abnormalities by congential or acquired factors, including congenital heart disease, acquired heart valve disease, cardiomyopathy. In recent years, interventional therapy in structural heart diseases has gradually matured and been widely applied in clinical practice. Due to the fragility of heart valves and valve related organizations, or the congenital dysplasia of valves, the complex interventional therapeutic procedures can cause valve-related complications. In this paper, the causes, prevention and treatment of valve-related complications induced by interventional therapy in structural heart diseases are introduced.