胆囊癌的发病率呈逐年上上升趋势,据国内资料统计,占全部消化道肿瘤的第5位。在美国,胆囊癌占消化道肿瘤的3%,而死亡率却居消化道肿瘤的第2位[1];导致死亡率高的原因之一是多数病例未能早期诊断,失去手术机会。由于胆囊癌缺乏特征性临床表现、常与结石、炎症并存,半数以上病例 The incidence of gallbladder cancer showed an upward trend year by year, according to domestic statistics, accounting for all gastrointestinal tumors in the first five. In the United States, gallbladder cancer accounts for 3% of gastrointestinal tumors, but mortality ranks second in gastrointestinal cancers [1]. One of the reasons leading to high mortality is that most cases fail to be diagnosed early and lose the chance of surgery. Due to the lack of characteristic clinical manifestations of gallbladder cancer, often with stones, inflammation coexist, more than half of cases