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目的:探讨肝硬化并发糖尿病的临床特点及相关因素。方法:对52例肝硬化并发糖尿病患者的相关因素进行回顾性分析。结果:肝源性糖尿病在不同年龄、肝病病程、肝炎病毒感染间差异有统计学意义,而不同民族、性别、肝功能分级间无统计学意义。易出现并发症。随肝功能恶化,空腹血糖升高,胰岛素水平增加,胰岛素敏感指数下降。结论:肝源性糖尿病主要继发于中老年肝硬化,症状不典型,易出现并发症,与病程、病毒感染有关,而与肝功能损害程度无明显关系。
Objective: To investigate the clinical features and related factors of cirrhosis complicated with diabetes. Methods: Retrospective analysis was made on the related factors of 52 patients with cirrhosis and diabetes. Results: Hepatic-type diabetes at different ages, duration of liver disease, hepatitis virus infection was significantly different, but different nationalities, gender, liver function grading was not statistically significant. Prone to complications. With deterioration of liver function, fasting blood glucose, insulin levels increased, decreased insulin sensitivity index. CONCLUSION: Hepatic-derived diabetes is mainly secondary to cirrhosis of the liver in middle-aged and elderly patients. The symptoms are not typical and complications are easily observed. It is related to the course of disease and viral infection, but not to the degree of liver damage.