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应用一组单克隆抗体，ＡＢＣ法对３０例体（股）癣病人外用血及皮损的郎格率细胞和Ｔ细胞亚群进行检测，结果表明病人外周血细胞，皮损中ＨＬＡ－ＤＲ＋细胞均高于正常对照（Ｐ＜０．０５～０．００１），细胞数目无明显改变（Ｐ＞０．０５），细胞在皮肤真菌病中可能递呈真菌抗原给Ｔ细胞。比率无明显改变（Ｐ＞０．０５），说明局部免疫功能基本正常。上述改变说明细胞免疫在皮肤真菌病的发病机理中起着重要作用。
A group of monoclonal antibodies and ABC method were used to detect the Langer rate cells and T cell subsets in 30 cases of patients with ringworm disease. The results showed that HLA-DR + cells in peripheral blood cells and lesions of patients Compared with the normal control group (P <0.05-0.001), the number of cells did not change significantly (P> 0.05). The cells could present fungal antigens to T cells in dermatomycosis. No significant change in the ratio (P> 0.05), indicating that the local immune function was normal. The above changes indicate that cellular immunity plays an important role in the pathogenesis of dermatophytosis.