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目的总结CIK细胞免疫治疗消化系统肿瘤临床疗效及心理护理经验。方法 2007年7月至2010年3月昆明医学院附属延安医院收治97例消化系统恶性肿瘤患者进行192次CIK细胞免疫治疗,对CIK细胞免疫治疗前的细胞制备、治疗时、治疗后不良反应观察进行记录,对疗效进行跟踪随访,同时对患者进行心理护理。结果 97例患者中,3例食管癌,治疗后主观症状改善明显。胰腺癌6例,有近期疗效4例。肝癌6例,有近期疗效5例。胆囊癌5例,有近期疗效4例。在CIK细胞免疫治疗的18例胃癌、41例结肠癌、18例直肠癌中,近期有效率分别为77.78%、65.8%和72.22%。患者能积极配合进行CIK细胞免疫治疗,使治疗获得满意的效果。结论 CIK细胞免疫治疗为综合治疗的有效手段之一,对提高疗效、改善生活质量有重要意义。
Objective To summarize the clinical efficacy and psychological nursing experience of CIK cell immunotherapy for digestive system tumors. Methods From July 2007 to March 2010, 97 cases of patients with digestive system malignancies were treated in Yan’an Hospital of Kunming Medical College for 192 CIK cell immunotherapy. Adverse reactions were observed after CIK cell immunotherapy before preparation, treatment and treatment Record, the follow-up of the efficacy of the same time, psychological care of patients. Results Of the 97 patients, 3 had esophageal cancer, and subjective symptoms improved significantly after treatment. 6 cases of pancreatic cancer, 4 cases of recent efficacy. 6 cases of liver cancer, 5 cases of recent efficacy. Gallbladder cancer in 5 cases, the recent curative effect in 4 cases. In 18 cases of gastric cancer, 41 cases of colon cancer and 18 cases of rectal cancer treated with CIK cell immunotherapy, the effective rates were 77.78%, 65.8% and 72.22% respectively. Patients can actively cooperate with CIK cell immunotherapy, so that treatment to obtain satisfactory results. Conclusion CIK cell immunotherapy is one of the effective methods for comprehensive treatment, which is of great significance to improve the curative effect and improve the quality of life.