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目的:探讨盐酸氨溴索在治疗喘息型慢性支气管炎急性发作的临床效果。方法:选择急性发作期喘息型慢性支气管炎患者90例,随机分为观察组和对照组。两组均常规应用抗生素、祛痰药及氨茶碱解痉平喘治疗。观察组在常规治疗基础上,给予盐酸氨溴索30mg,加入5%葡萄糖100ml,于30min内缓慢静脉输注,2次/d,两组疗程均为10d。结果:观察组总有效率93.0%,与对照组总有效率70.2%比较差异有统计学意义(P<0.05),血气(PaO2、PaCO2、PH)和肺功能FEV1%、FVC、FEV1/FVC(%)、PEF明显改善,优于对照组。结论:在常规治疗基础上,加盐酸氨溴索治疗喘息性慢性支气管炎,临床效果显著,值得推广使用。
Objective: To investigate the clinical efficacy of ambroxol hydrochloride in the treatment of acute episodes of asthmatic chronic bronchitis. Methods: Ninety patients with asthmatic chronic bronchitis were randomly divided into observation group and control group. Both groups were routinely used antibiotics, expectorants and aminophylline antispasmodic asthma treatment. On the basis of routine treatment, the observation group was given ambroxol hydrochloride 30mg, 5% glucose 100ml, slow intravenous infusion within 30min, twice a day for 10 days. Results: The total effective rate was 93.0% in the observation group and 70.2% in the control group, with statistical significance (P <0.05). PaO2, PaCO2, PH and pulmonary function FEV1%, FVC, FEV1 / FVC %), PEF significantly improved, better than the control group. Conclusion: On the basis of conventional treatment, ambroxol hydrochloride in the treatment of asthmatic chronic bronchitis, the clinical effect is significant, it is worth promoting the use of.