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目的探讨强负荷训练对新兵心肌的影响和可能的机制。方法随机抽取2012年1月某部入伍1个月健康男性新兵200名,随机分为A组(5 km越野跑)和B组(仅参加日常的队列和一般强度训练),每组100名。两组分别于训练当日晨采集静脉血检测血清肌钙蛋白T(cTnT)、B型钠尿肽(BNP)、心型脂肪酸结合蛋白(H-FABP)和C反应蛋白(CRP),并于训练后即刻检测BNP和CRP,训练后次日晨检测cTnT和H-FABP。结果两组新兵运动前各项指标均在正常范围,A组运动后cTnT、BNP、H-FABP和CRP较运动前明显升高,且明显高于B组,B组仅cTnT运动后高于运动前(P<0.01,P<0.05)。结论新兵入伍后首次5 km越野跑可导致心肌微损伤,其原因可能与首次强负荷训练导致心肌炎症和心脏室壁张力增高有关。
Objective To investigate the effect of intensive training on recruits cardiac muscle and its possible mechanism. Methods A total of 200 male recruits were enrolled in January 2012. They were randomly divided into group A (5 km trail running) and group B (only participated in daily cohort and general intensity training), with 100 in each group. Venous blood samples were collected for venous blood glucose test, serum BNP, H-FABP and C-reactive protein (CRP) BNP and CRP were detected immediately and cTnT and H-FABP were measured the next morning after training. Results The scores of cTnT, BNP, H-FABP and CRP in group A were significantly higher than those before exercise, and were significantly higher than those in group B. In group B, cTnT was higher than that in group C Before (P <0.01, P <0.05). Conclusions The first 5 km of trail running after enlisted recruits may lead to myocardial micro-injury, which may be related to the first severe exercise-induced myocardial inflammation and increased cardiac wall tension.