论文部分内容阅读
[作用特点] 本品为四环类广谱抗菌素,其抗菌谱和抗菌作用与四环素类似,对肺炎球菌、乙型链球菌等活性较强。与甲氧苄氨嘧啶(TMP)4:1联合应用能增强本品对肺炎球菌、流感杆菌的抗菌活性2~8倍。据报道,本品也有抗病毒活性。本品在水中溶解度很大,口服后吸收迅速。一次口服60万单位,3小时血浓度最高,有效血浓度可维持12小时以上。本品主要以活性型经尿排泄。
[Features] This product is tetracycline broad-spectrum antibiotics, antibacterial spectrum and antibacterial effect similar to tetracycline, Streptococcus pneumoniae, B streptococci and other activities. And the combination of trimethoprim (TMP) 4: 1 can enhance the antimicrobial activity of this product on pneumococcus, influenza bacilli 2 to 8 times. It is reported that this product also has antiviral activity. This product is highly soluble in water, absorbed rapidly after oral administration. An oral 600,000 units, 3 hours maximum blood concentration, effective blood concentration can be maintained more than 12 hours. This product is mainly active excretion of urine.