论文部分内容阅读
本文介绍VCR与DDP或CTX合用治疗鼻咽癌44例,共中晚期(ⅢⅣ期)病例居多数(占75％),病理类型以低分化鳞癌最多(占84.1％)。 治疗方法分PO和CO两组,PO方案是第一周每天DDP20mg,iv,连用5天,第6、7天用VCR 1mg,iv,第二周停药,第三周重复用药,一疗程总量DDP200mg,VCR 4mg。CO方案是先用VCR 1mgiv,继用CTX1gm滴注,每周2次,连用3周,一疗程总量VCR 6mg,CTX 6gm。 治疗结果:PO和CO方案总有效率分别为86.4％和77.3％,从显效病例作比较,PO方案13例(59.17)优于CO方案6例(27.3％),卡方测定有显著差异。
This article describes the combination of VCR and DDP or CTX in the treatment of 44 cases of nasopharyngeal carcinoma, a total of middle and late (III IV) cases of majority (75%), pathological type of poorly differentiated squamous cell carcinoma (84.1%). The treatment was divided into PO and CO groups. The PO regimen was DDP 20mg,iv for 5 days in the first week, VCR 1mg in the 6th and 7th days, iv, withdrawal in the second week, repeated medication in the third week, one course of treatment Amount DDP 200mg, VCR 4mg. The CO regimen was to use VCR 1 mgiv, followed by CTX1 gm infusion, 2 times per week for 3 weeks, and the total VCR 6 mg and CTX 6 gm for one course of treatment. Treatment results: The total effective rates of PO and CO were 86.4% and 77.3%, respectively. Compared with the marked cases, 13 cases (59.17) were better in the PO regimen than in the CO regimen (27.3%). There was a significant difference in the chi-square test.