本文前瞻性研究了患 SLE 或 SLE 样综合征妇女新生91例婴儿的临床情况,并对母亲妊娠前12周的血清进行了抗 Ro、La、RNP 抗体的检测。新生儿有发疹和先天性心脏传导阻滞者诊断为新生儿狼疮(NL),若仅有血小板减少或其他心脏疾患而无心律失常者则为可疑 NL,抗 Ro 及(或)抗 La 抗体阳性母亲所生的新生儿均作心电图和血小板计数检查。结果:在23%受试母亲中发现抗 Ro 和抗 Ro/ This study prospectively investigated the clinical status of 91 newborn infants with SLE-like syndrome or SLE-like syndrome and tested anti-Ro, La and RNP antibodies against the serum of mothers 12 weeks before pregnancy. Newborns with measles and congenital heart block are diagnosed with neonatal lupus (NL), suspicious NL if only thrombocytopenia or other heart disease without arrhythmia, anti-Ro and / or anti-La antibody Neonates born to positive mothers were examined by electrocardiogram and platelet count. Results: The anti-Ro and anti-Ro /