【摘 要】
:
AIM: To compare the preservation of non-heart beating donor (NHBD) livers in cold histidine-trytophan ketoglutarate (HTK) solution and extracorporeal liver perf
【机 构】
:
Department of Surgery,Institute of Organ Transplantation
论文部分内容阅读
AIM: To compare the preservation of non-heart beating donor (NHBD) livers in cold histidine-trytophan ketoglutarate (HTK) solution and extracorporeal liver perfusion (ECLP).METHODS: Livers harvested from health pigs were stored for 10 h in cold HTK solution (group A, n=4)or perfused with oxygenated autologous blood at eody temperature (group B, n = 4). Both groups were then tested on the circuit for 4 h. Bile production,hemodynamic parameters, hepatocyte markers andreperfusion injury of extracorporeal livers were testedin each group. Liver tissues from each group wereexamined at the end of reperfusion.RESULTS: At 1, 2, 3 and 4 h after reperfuSion, bileproduction, hemodynamic parameters, hepatocytemarkers and reperfusion injury of livers in group A werestatistically different from those in group B (P < 0.05 orP < 0.01).CONCLUSION: ECLP is better than HTK solution topreserve NHBD livers. ECLP can assess the graft viabilitybefore liver transplantation.
其他文献
A 69-year-old man was diagnosed as having myasthenia gravis (MG) in September 2004, and treated with thymectomy and prednisolone. He was then diagnosed as havin
Background Evidence showed that both myocardium and blood vessels were damaged in dilated cardiomyopathy (DCM).However,the changes in arterial compliance,serum
MYC is an oncogene involved in cell cycle regulation, cell growth arrest, cell adhesion, metabolism, ribosome biogenesis, protein synthesis, and mitochondrial f
Background Remodeling of the anterior cruciate ligament (ACL) graft usually takes longer than expected. Gene therapy offers a radical different approach to remo
Multilevel aortic disease presents a formidable challenge for vascular surgeons. In the past, multilevel aortic surgery was performed simultaneously or subseque
Seasonal influenza is a highly contagious, acute respiratory illness that affects people of all ages. The major pathogens, influenza A viruses, are classified i
To explore the better prodrug of 4-aminosalicylic acid (4-ASA) with higher activity and less side effects against the inflammatory bowel disease.4-ASA,after a s
AIM: To observe the therapeutic effects of new traditional Chinese medicine (TCM) therapy on coagulation disorder and accompanying intractable jaundice in HBV-r
Background Calcitonin gene-related peptide (CGRP) is the predominant neurotransmitter in capsaicin-sensitive sensory nerves. Participation of CGRP in hypertensi