肝胆系统与皮肤之间有密切的关系,肝胆疾病可以引起皮肤病,肝脏的合成、排泄或调节功能的异常可以导致皮肤及其附件的结构与功能变化,如黄疸、瘙痒、色素异常及指甲、毛发等的改变。另一方面,皮肤病也可以引起肝脏的异常,如银屑病性红皮病患者血清蛋白及肝功能经常不正常。有些疾病,皮肤、肝脏同时受累,如组织细胞增生症X、小儿丘疹性肢端皮炎(Gianotti-Crosti 综合征)以及某些遗传病如精氨酸琥珀酸尿症等。本文就肝胆疾病所引起的皮肤表现综述 Hepatobiliary system and the skin are closely related to the liver and gallbladder disease can cause skin diseases, liver synthesis, excretion or regulatory dysfunction can lead to changes in the structure and function of the skin and its annexes, such as jaundice, itching, pigmentary abnormalities and nails, Hair and other changes. On the other hand, skin disorders can also cause liver abnormalities, such as psoriatic erythroderma serum protein and liver function often not normal. Some diseases, skin, liver at the same time, such as histiocytosis X, papular acral dermatitis (Gianotti-Crosti syndrome), and some genetic diseases such as arginine succinateuria and so on. This article summarizes the skin manifestations caused by hepatobiliary diseases