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目的观察布地奈德、沙丁胺醇溶液联合驱动雾化吸入治疗毛细支气管炎的疗效。方法将临床确诊为毛细支气管炎患儿108例随机分为两组:观察组54例(布地奈德和沙丁胺醇溶液雾化吸入组)和对照组54例(地塞米松静脉滴注组)。观察用药前后患儿症状、体征(咳嗽、气促、喘憋、及肺部哮鸣音)改善情况。结果两组患儿均未发现与用药明显相关的不良反应,观察组显效率明显高于对照组,二者差异有显著性。结论布地奈德、沙丁胺醇溶液联合驱动雾化吸入治疗毛细支气管炎有协同作用,可以明显改善症状及缩短病程,提高治愈率,值得临床推广。
Objective To observe the curative effect of budesonide and albuterol combined with aerosol inhalation on bronchiolitis. Methods One hundred and eighty children with bronchiolitis diagnosed clinically were randomly divided into two groups: observation group (n = 54), budesonide and salbutamol inhalation group (n = 54) and control group (n = 54). Observed before and after treatment of children with symptoms, signs (cough, shortness of breath, wheezing, and lung wheeze) to improve the situation. Results The two groups of children did not find any significant adverse drug reaction, the observation group was significantly higher than the efficiency of the control group, the difference was significant. Conclusion Budesonide and salbutamol combined with aerosol inhalation in the treatment of bronchiolitis have synergistic effect, which can significantly improve the symptoms and shorten the course of disease, and improve the cure rate, which is worthy of clinical promotion.