本文采用微量间接免疫荧光方法首次在广东省大埔县、平远县和梅县１０１２名健康人中进行了斑点热群立克次体感染的血清流行病学调查。结果表明，三县西伯利亚立克次体的感染率平均为１６９９％，其中大埔县为２８４７％、平远县为２０４６％、梅县为６８％；康氏立克次体的感染率平均为２２６３％，其中大埔县为２７７８％、平远县为１３４２％、梅县为２５５９％；三县小蛛立克次体的感染率平均为１８２８％，其中大埔县为２１８８％、平远县为１８８０％、梅县为１５４９％。健康人群血清中斑点热群立克次体ＩｇＧ抗体阳性率经统计学处理未见有性别、年龄和职业的差别。上述结果提示在广东省大埔县、平远县和梅县可能存在有斑点热的自然疫源地 This article for the first time using indirect immunofluorescence method in Tai Po County, Guangdong Province, Pingyuan and Meixian 1012 healthy people were spotted fever group Rickettsial Serum Epidemiological Investigation. The results showed that the infection rate of Rickettsia in three counties averaged 1699%, of which 2847% in Dapu County, 2046% in Pingyuan County and 68% in Meixian County. The infection rate of the second body was 2263% on average, with 2778% in Dapu County, 1342% in Pingyuan County and 2559% in Meixian County. The average infection rates of Rickettsia 1828%, of which 2188% in Dapu County, 1880% in Pingyuan County and 1549% in Meixian County. The positive rate of Rickettsia IgG antibody in the serum of the healthy people was no statistical difference was found in gender, age and occupation. The above results suggest that there may be plague-prone natural foci in Dapu County, Pingyuan County and Meixian County in Guangdong Province