论文部分内容阅读
目的观察不同治疗方案治疗具有生育要求的多囊卵巢综合征患者的临床疗效。方法 298例具有生育要求的多囊卵巢综合征患者,按治疗方案不同分为研究组(173例)和对照组(125例)。研究组行个性化方案治疗,对照组行常规方法治疗,治疗周期结束后评价两组治疗效果。结果治疗前两组促卵泡激素(FSH)、促黄体生成素(LH)、睾酮(T)、结合球蛋白(SHBG)及游离睾酮指数(FAI)表达水平比较差异均无统计学意义(P>0.05);治疗后研究组FSH、LH、T、FAI表达水平均较低于对照组,SHBG水平高于对照组,差异均有统计学意义(P<0.05)。研究组排卵率为87.9%,妊娠率为58.4%,高于对照组的68.8%、41.6%,差异均有统计学意义(P<0.05)。结论采用个性化方案对具有生育要求的多囊卵巢综合征患者实施治疗,能够改善患者激素异常表达,提高患者的排卵率和妊娠率。
Objective To observe the clinical effects of different treatment regimens in patients with polycystic ovary syndrome who have fertility requirements. Methods 298 patients with polycystic ovary syndrome who had fertility requirements were divided into study group (173 cases) and control group (125 cases) according to different treatment plans. The study group was treated with personalized program, while the control group was treated with routine method. After the treatment period, the curative effect of both groups was evaluated. Results There were no significant differences in FSH, LH, T, SHBG and FAI before treatment (P> 0.05). After treatment, the expression levels of FSH, LH, T and FAI in the study group were lower than those in the control group, while the levels of SHBG in the study group were higher than those in the control group (P <0.05). The study group ovulation rate was 87.9%, pregnancy rate was 58.4%, higher than the control group 68.8%, 41.6%, the difference was statistically significant (P <0.05). Conclusions The individualized treatment of polycystic ovary syndrome patients with fertility requirements can improve the abnormal expression of hormone and improve the ovulation rate and pregnancy rate of the patients.